Physiological and pharmacological properties of GABA-ergic gain modulation of canine ventral respiratory group (VRG) neurons
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Responses of ventral respiratory group neurons of the cat to natural vestibular stimulation.
Stimulation of vestibular otolith afferents by fore-aft tilt (pitch) elicits changes in activity of nerves innervating respiratory muscles, including the diaphragm, abdominal muscles, and tongue musculature. To determine the role of ventral respiratory group (VRG) neurons in producing these vestibular-respiratory responses, the activity of VRG neurons was recorded during natural vestibular stim...
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متن کاملDifferential modulation of respiratory neuronal discharge patterns by GABA(A) receptor and apamin-sensitive K(+) channel antagonism.
The discharge patterns of respiratory neurons of the caudal ventral respiratory group (cVRG) appear to be subject to potent GABAergic gain modulation. Local application of the GABA(A) receptor antagonist bicuculline methochloride amplifies the underlying discharge frequency (F(n)) patterns mediated by endogenous excitatory and inhibitory synaptic inputs. Gain modulation can also be produced by ...
متن کاملJN-00761-2002.R1 Differential Processing Of Excitation by GABAergic Gain Modulation in Canine Caudal Ventral Respiratory Group Neurons
words: 270 Text pages: 17 Figures: 7 (FINAL ACCEPTED VERSION) Copyright (c) 2002 by the American Physiological Society. Articles in PresS. J Neurophysiol (October 30, 2002). 10.1152/jn.00761.2002
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